Publications

 To view the most up-to-date list of publications, please visit Google Scholar Profile

Click here

 

 

20. Isaac, I., Patel, L., Yun, D., Park, S., & Bhattacharya, C. (2025). Endogenous Corticosteroid Derived Lipid Nanoparticles (Cortico LNPs) Enable Selective mRNA Delivery to the Spleen. Small (Weinheim an der Bergstrasse, Germany), e03034. Advance online publication. 

 

 

19. Evereux, V., Saha, S., Bhattacharya, C., Park, S. Characterization of time-dependent viscoelastic behaviors of alginate-calcium chloride hydrogels for bioprinting applications. Biomed. Eng. Lett. (2025). 

 

 

18. Isaac, I., Patel, L., Tran, N., Singam, A., Yun, D., Guha, P., Park, S., & Bhattacharya, C. (2025). Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas. Advanced materials (Deerfield Beach, Fla.), e2507657. Advance online publication. 

 

 

17. Singam, A., Gopakumar, N., Chauhan, A., Ramirez, K., Kim, J. H., Bhattacharya, C., Chen, J., Kim, D. H., & Park, S. (2025). Unveiling Lipid Droplet Transport Dynamics as Biomarkers of Senescence Using Label-Free, Time-Lapse Holotomography. Aging and disease, 10.14336/AD.2024.1408. Advance online publication. 

 

16. Isaac, I., Shaikh, A., Bhatia, M., Liu, Q., Park, S., & Bhattacharya, C. (2024). Tetrahydropyrimidine Ionizable Lipids for Efficient mRNA Delivery. ACS nano, 18(42), 29045–29058. 

 

15. Isaac, I., Bhatia, M., & Bhattacharya, C. (2024). Recent Advances in Biomaterials for mRNA Delivery to Immune Cells. ACS applied bio materials, 7(8), 5136–5146. 

 

14. Singam,A., Bhattacharya, C., & Park, S. (2024). Aging-related changes in the mechanical properties of single cells. Heliyon, 10(12), e32974.

 

 

From Postdoc and Graduate Work

 

13. Bose, S., Volpatti, L. R., Thiono, D., Yesilyurt, V., McGladrigan, C., Tang, Y., Facklam, A., Wang, A., Jhunjhunwala, S., Veiseh, O., Hollister-Lock, J., Bhattacharya, C., Weir, G. C., Greiner, D. L., Langer, R., & Anderson, D. G. (2020). A retrievable implant for the long-term encapsulation and survival of therapeutic xenogeneic cells. Nature biomedical engineering, 4(8), 814–826. 

 

12. Pawar, N. J., Wang, L., Higo, T., Bhattacharya, C., Kancharla, P. K., Zhang, F., Baryal, K., Huo, C. X., Liu, J., Linhardt, R. J., Huang, X., & Hsieh-Wilson, L. C. (2019). Expedient Synthesis of Core Disaccharide Building Blocks from Natural Polysaccharides for Heparan Sulfate Oligosaccharide Assembly. Angewandte Chemie (International ed. in English), 58(51), 18577–18583. 

 

11. Paolini, M. S., Fenton, O. S., Bhattacharya, C., Andresen, J. L., & Langer, R. (2019). Polymers for extended-release administration. Biomedical microdevices, 21(2), 45. 

 

10. Kowalski, P. S., Bhattacharya, C., Afewerki, S., & Langer, R. (2018). Smart Biomaterials: Recent Advances and Future Directions. ACS biomaterials science & engineering, 4(11), 3809–3817. 

*equal contribution

 

9. Daskalova, S. M., Bhattacharya, C., Dedkova, L. M., & Hecht, S. M. (2017). Probing the Flexibility of the Catalytic Nucleophile in the Lyase Catalytic Pocket of Human DNA Polymerase β with Unnatural Lysine Analogues. Biochemistry, 56(3), 500–513. 

 

8. Talukder, P., Chen, S., Roy, B., Yakovchuk, P., Spiering, M. M., Alam, M. P., Madathil, M. M., Bhattacharya, C., Benkovic, S. J., & Hecht, S. M. (2015). Cyanotryptophans as Novel Fluorescent Probes for Studying Protein Conformational Changes and DNA-Protein Interaction. Biochemistry, 54(51), 7457–7469. 

 

7. Yu, Z., Paul, R., Bhattacharya, C., Bozeman, T. C., Rishel, M. J., & Hecht, S. M. (2015). Structural features facilitating tumor cell targeting and internalization by bleomycin and its disaccharide. Biochemistry, 54(19), 3100–3109. 

 

6. Yu, X., Talukder, P., Bhattacharya, C., Fahmi, N. E., Lines, J. A., Dedkova, L. M., LaBaer, J., Hecht, S. M., & Chen, S. (2014). Probing of CD4 binding pocket of HIV-1 gp120 glycoprotein using unnatural phenylalanine analogues. Bioorganic & medicinal chemistry letters, 24(24), 5699–5703. 

 

5. Madathil, M. M., Bhattacharya, C., Yu, Z., Paul, R., Rishel, M. J., & Hecht, S. M. (2014). Modified bleomycin disaccharides exhibiting improved tumor cell targeting. Biochemistry, 53(43), 6800–6810. 

 

4. Schroeder, B. R., Ghare, M. I., Bhattacharya, C., Paul, R., Yu, Z., Zaleski, P. A., Bozeman, T. C., Rishel, M. J., & Hecht, S. M. (2014). The disaccharide moiety of bleomycin facilitates uptake by cancer cells. Journal of the American Chemical Society, 136(39), 13641–13656. 

 

3. Bhattacharya, C., Yu, Z., Rishel, M. J., & Hecht, S. M. (2014). The carbamoylmannose moiety of bleomycin mediates selective tumor cell targeting. Biochemistry, 53(20), 3264–3266. 

 

2. Chen, S., Fahmi, N. E., Bhattacharya, C., Wang, L., Jin, Y., Benkovic, S. J., & Hecht, S. M. (2013). Fluorescent biphenyl derivatives of phenylalanine suitable for protein modification. Biochemistry, 52(47), 8580–8589. 

 

1. Chen, S., Fahmi, N. E., Wang, L., Bhattacharya, C., Benkovic, S. J., & Hecht, S. M. (2013). Detection of dihydrofolate reductase conformational change by FRET using two fluorescent amino acids. Journal of the American Chemical Society, 135(35), 12924–12927.