August 2025
Bhattacharya Lab’s ENDO paper ”Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas” is featured by Scienmag ‘Decoding Organ-Specific Drug Delivery: A Breakthrough in Targeted Therapy‘
August 2025
Bhattacharya Lab’s ENDO paper ”Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas” is featured by Phys.Org – Researchers develop nanoparticles that deliver mRNA directly to the pancreas
August 2025
Bhattacharya Lab’s ENDO paper ”Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas” is featured by UNLV News.
July 2025
Bhattacharya Lab publishes latest research in Small led by graduate student Ivan Isaac, entitled ”Endogenous Corticosteroid Derived Lipid Nanoparticles (Cortico LNPs) Enable Selective mRNA Delivery to the Spleen”
In this study, we introduce a new class of lipid nanoparticles (LNPs), endogenous corticosteroid-derived LNPs (cortico-LNPs), in which the cholesterol component is replaced with endogenous corticosteroids, resulting in redirection from the liver to the spleen.
June 2025
Bhattacharya Lab publishes latest research in Advanced Materials led by graduate student Ivan Isaac, entitled ”Reengineering Endogenous Targeting Lipid Nanoparticles (ENDO) for Systemic Delivery of mRNA to Pancreas”
In this study, we introduce ENDO (Endogenous Targeting Lipid Nanoparticles), a groundbreaking platform that achieves intravenous mRNA delivery to the pancreas with an unprecedented 99% selectivity.
October 2024
Chandra was featured by PhRMA Foundation in a Q&A session to chat about Designing a Novel Platform to Improve CAR T Cell Therapy
October 2024
Bhattacharya lab publishes first article in ACS Nano led by Ivan Isaac, entitled “Tetrahydropyrimidine Ionizable Lipids for Efficient mRNA Delivery”
In this article, we introduce a novel, facile, catalyst-free, and versatile one-pot multicomponent reaction (MCR) to develop a library of ionizable lipids featuring a pharmacologically significant tetrahydropyrimidine (THP) backbone, tailored for enhanced mRNA delivery.
July 2024
Bhattacharya lab publishes first paper in ACS Applied Bio Materials entitled “Recent Advances in Biomaterials for mRNA Delivery to Immune Cells” (review) led by PhD student Ivan Isaac
October 2023
Chandra interviewed by KNPR to talk about University continues top-tier research for betterment of Las Vegas
August 2023
Bhattacharya Lab was featured by UNLV press ”Inside the Bhattacharya Lab‘‘
January 2023
The laboratory is officially open!
March 2020
Just Doing Experiments? Well, Ones that May Have Life-Saving Potential
Early-Career Scientists: JDRF Ignites Researchers’ Hopes and Careers
Strengthening Type 1 Diabetes Science by Building Careers
Meet the Scientist: Chandra Bhattacharya
Using chemistry to develop what may be life-changing for people with T1D: “smart insulin.”
December 2017
Chandra receives Juvenile Diabetes Research Foundation (JDRF) Postdoctoral Fellowship for her work on the development of glucose-responsive material for smart insulin. These systems would respond quickly to elevations in blood glucose, deliver an appropriate amount of insulin, and terminate delivery once normoglycemia is restored.
